I'm still researching these slot machine payouts in different areas, and this month's Strictly Slots magazine has a list of areas in Nevada along with their corresponding payback percentages. I've listed some of that information below, and maybe it will help you pick out a place to play. These are the payouts for the nickel slot machines:

The Boulder Strip 94% (This was the top payout percentage.)
Mesquite 93.5%
Lake Tahoe 92.4%
North Las Vegas 92.3%
Reno 92.2%
Downtown Las Vegas 90.6%
Laughlin 89.3%
Las Vegas Strip 88.8%

After looking these numbers over, I think next time I'm in Vegas, I'll play at the Boulder Strip or Downtown, and just visit the Strip casinos for the shows and stuff. Although the Las Vegas Strip was the big winner for $100 slots, with a payout of 95.4%. At the same time, I can't afford to make $100 slot pulls.

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Slotty McSlots